Genetic engineering consists of selecting, inserting, or removing individual genes in order to manipulate the genome of an organism. In agriculture and animal husbandry selective breeding to obtain preferred strains has been practiced for millennia. Modern genetic engineering adds chemical and mechanical methods for more sophisticated results.
In agriculture the genomes of plants are altered by genetic engineering to confer resistance to blight or resistance to herbicides in order to eliminate weeds while preserving the crops. Tomato genomes, for example, can be modified so as to stall final ripening during transport to market and then ripen just prior to going on sale.
Such techniques dramatically increase the percentage of produce that becomes marketable. In Europe and other parts of the world popular movements against genetically modified foods (GMFs) have arisen. Fearing unknown possible health effects, opponents of GMFs lobby for accurate labeling so that the market can freely choose whether to consume them or not.
The engineering of farm animal genomes has two purposes. One is to obtain preferred strains of livestock, especially beef cattle. The other is to produce foods or pharmaceuticals for human consumption. An example of the latter case is the insertion of a human gene into a sheep genome to produce in the animal’s milk a certain protein usable for treatment of a human disease. This use of animals for human betterment is itself controversial, with opponents arguing that turning animals into a means for human ends violates animal dignity.
To date, the genetic engineering of human genomes in the reproduction process has been limited to gene selection; it has not included gene insertion or removal. When in vitro multiple fertilized ova are examined, only those with the preferred genome may be implanted in the mother’s uterus.
This process is typically employed to eliminate known deleterious genes such as that for cystic fibrosis. In somatic therapy on living persons, however, more than selection is being tried. Genes that produce healthy blood have been inserted into bone marrow cells. Attempts are being made to send ‘knock out’ genes into cancer tumors to turn off tumor growth by turning off telomerase activity.
An implicit theological issue that arises more often in the wider cultural debate than within specific religious communities is naturalism. Naturalism is the belief that nature apart from intervention by human technology is the source of value. Genetic engineering is a form of technology altering the natural world that people have inherited from evolutionary history.
The Promethean question arises implicitly: Is the natural world the source of human value, or, on the basis of humanly superimposed purposes, do people have the right to manipulate nature to meet these purposes? Much of the energy driving opposition to GMFs derives from natural-ism. A similar naturalism is implicit in theological arguments, which presume that God’s will is manifest in the genetic lottery resulting from reproduction rather than through deliberate selection in vitro of the genetic code of future children.
The Promethean question also arises with genetic futurism. As the present generation manipulates plant, animal, and human genomes, will this place humans in the position of guiding our evolutionary future? Does the human race possess the wisdom to choose a wholesome future or, like Prometheus of ancient Greek tragedy, will humans overstep their finite bounds and create an irreparable tragedy?
Conservative theologians along with naturalist advocacy groups wish to put the brakes on genetic engineering and let nature take its course; whereas other religious leaders foresee immense benefits for health and wellbeing to be gained through genetic technology and contend that the human race must steward scientific advance.
(Author is a lecturer in HED)
Leave a comment